Predicting the impact of proton beam therapy technology on pulmonary toxicities for locally advanced lung cancer patients enrolled on the Proton Collaborative Group prospective clinical trial

CONCLUSION: In the largest analysis of prospectively enrolled patients with lung cancer assessing pulmonary toxicities from proton therapy to date, advanced machine learning methods have identified that PBS, abdominal compression, and lower normal lung doses can lead to significantly lower probability of developing grade ≥2 pneumonitis or dyspnea.PMID:38000701 | DOI:10.1016/j.ijrobp.2023.11.026

Source: Health Physics - November 24, 2023 Category: Physics Authors: Gilmer Valdes Jessica Scholey Tomi Nano Efstathios D Gennatas Pranshu Mohindra Nasir Mohammed Jing Zeng Rupesh D Kotesha Lane R Rosen John Chang Henry K Tsai James J Urbanic Carlos E Vargas Nathan Y Yu Lyle H Ungar Eric Eaton Charles B Simone Source Type: research