Fatal Human Neurologic Infection Caused by Pigeon Avian Paramyxovirus-1, Australia

We report a fatal case of neurologic disease in a 2-year-old immunocompromised child in Australia. Metagenomic sequencing and histopathology identified the causative agent as the pigeon variant of APMV-1. This diagnosis should be considered in neurologic conditions of undefined etiologies. Agnostic metagenomic sequencing methods are useful in such settings to direct diagnostic and therapeutic efforts.PMID:37987582 | DOI:10.3201/eid2912.230250

Source: Emerging Infectious Diseases - November 21, 2023 Category: Infectious Diseases Authors: Siobhan Hurley John Sebastian Eden John Bingham Michael Rodriguez Matthew J Neave Alexandra Johnson Annaleise R Howard-Jones Jen Kok Antoinette Anazodo Brendan McMullan David T Williams James Watson Annalisa Solinas Ki Wook Kim William Rawlinson Source Type: research