Regional anesthesia and sickle cell crisis in pediatric patients: An educational-focused review

DISCUSSION: The available literature, albeit all retrospective or anecdotal, suggests the potential utility of regional anesthesia to treat pain in patients with SCD. Additional benefits have included avoidance of the potential deleterious physiologic effects of systemic opioids and in one case series, an improvement in respiratory function as judged by pulse oximetry. The anecdotal and retrospective nature of the available reports with an absence of prospective trials limits the evidence based medicine available from which to develop to guidlines for the optimal local anesthetic agent to use, its concentration, the rate of infusion, and the choice of adjunctive agents.PMID:37983941 | DOI:10.1111/pan.14801
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Source Type: research