Shikonin Suppresses Cell Tumorigenesis in Gastric Cancer Associated with the Inhibition of c-Myc and Yap-1

CONCLUSION: This study showed protooncogenes c-Myc and Yap-1 to be the core target genes of shikonin on gastric cancer cells. Shikonin may suppress gastric cancer cells by inhibiting the protooncogenes c-Myc and Yap-1. This suggests that shikonin may be a good candidate for the treatment of gastric cancer.PMID:37957853 | DOI:10.2174/0113862073254088231020082912
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Source Type: research