Therapeutic potential of human iPS cell-derived cardiac tissue in an ischemic model with unloaded condition mimicking left ventricular assist device

This study aimed to explore the therapeutic potential of hiPSC-derived cardiac tissues (HiCTs) in the emerging approach of "Bridge to recovery (BTR)" for severe heart failure with ventricular assist devices (VADs). We utilized a rat model of heterotopic heart transplantation (HTx) to mimic VAD support and heart unloading.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Source Type: research