Protocol for a randomized controlled trial to reduce pediatric anesthesia emergence delirium by titration of sevoflurane anesthesia using brain function monitoring

DiscussionAnesthesia management with proactive use of brain function monitoring is expected to reduce exposure to sevoflurane without compromising surgical anesthesia. We expect this reduced exposure should help prevent PAED. Routinely administering what may be considered standard levels of anesthetic such as 1.0 MAC sevoflurane may be excessive and potentially associated with unfavorable sequelae such as PAED.Trial registrationJapan Registry of Clinical Trials (jRCT) jRCTs032210248. Prospectively registered on 17 August 2021.
Source: Trials - Category: Research Source Type: clinical trials