Cancers, Vol. 15, Pages 5412: Extracranial Germ Cell Tumors in Children: Ten Years of Experience in Three Children & rsquo;s Medical Centers in Shanghai

Conclusions: The clinical features of GCTs in Chinese pediatrics are similar to those reported in children in Europe and America. The age distribution of pathological types and primary sites in GCTs reflect the developmental origin of type I and type II GCTs transformed from mismigration primordial germ cells (PGCs). Optimizing the current platinum-based chemotherapy regimens and exploring the treatment strategies for MGCTs of the mediastinum are future research directions.

Source: Cancers - November 14, 2023 Category: Cancer & Oncology Authors: Shayi Jiang Kuiran Dong Kai Li Jiangbin Liu Xin Du Can Huang Yangyang Jiao Yali Han Jingwei Yang Xuelian Liao Yanhua Li Ting Zhang Shanshan Li Zhibao Lv Yijin Gao Tags: Article Source Type: research