Design, In Silico Molecular Docking, and ADMET Prediction of Amide Derivatives of Chalcone Nucleus as EGFR Inhibitors for the Treatment of Cancer

CONCLUSION: Molecules AC9 and AC19 showed good docking scores and a promising ADMET profile. In the future, these derivatives can be further evaluated for wet lab studies and determination of their biological activity.PMID:37921215 | DOI:10.2174/0115701638263890231027071518

Source: Current Drug Discovery Technologies - November 3, 2023 Category: Drugs & Pharmacology Authors: Shital M Patil Vrushali Randive Indrani Mahadik Kalyani Asgaonkar Source Type: research