Effectiveness of perioperative chemotherapy and radical cystectomy in treating bladder cancer

CONCLUSIONS: We report real-world outcomes from a large cohort of muscle-invasive bladder cancer patients undergoing surgical treatment with/out perioperative chemotherapy. Pathologic response rates to pre-surgical chemotherapy were modest and led to clinical benefit only in cT2 patients. Adjuvant chemotherapy provided survival benefit for pathologically advanced MIBC patients irrespective of pT/N staging.PMID:37880002 | DOI:10.1016/j.urolonc.2023.09.017

Source: Urologic Oncology - October 25, 2023 Category: Urology & Nephrology Authors: Roger Li Shreyas Naidu Wenyi Fan Kyle Rose Heather Huelster George Daniel Grass Aram Vosoughi Jasreman Dhillon Youngchul Kim Shilpa Gupta Rohit K Jain Jingsong Zhang Logan Zemp Alice Yu Michael A Poch Philippe E Spiess Julio Pow-Sang Scott M Gilbert Wade Source Type: research