Murine Malaria Model: Ketoconazole Preventing Malaria while Proguanil and Sulfadoxine/Pyrimethamine Protected against Malaria-associated Anemia and Kidney Damage

CONCLUSION: Ketoconazole possesses prophylactic antimalarial activity with associated dose-related renal impairment. Sulfadoxine/pyrimethamine demonstrated renoprotective potentials, while PRG prevented malaria-associated anemia.PMID:37881078 | DOI:10.2174/0118715265239831231017080840

Source: Infectious Disorders Drug Targets - October 26, 2023 Category: Infectious Diseases Authors: Akeem Ademola Ayankunle Samuel Olumide Faniran Ojurongbe O Adekunle O C Source Type: research