Activation of BZW1 by CEBPB in macrophages promotes eIF2 α phosphorylation-mediated metabolic reprogramming and endoplasmic reticulum stress in MRL/lpr lupus-prone mice

CONCLUSION: Transcriptional activation of BZW1 by CEBPB promoted phosphorylation of eIF2α to promote macrophage glycolysis and endoplasmic reticulum stress in the development of LN.PMID:37828427 | PMC:PMC10571419 | DOI:10.1186/s11658-023-00494-1

Source: Cellular and Molecular Biology Letters - October 12, 2023 Category: Biochemistry Authors: Huimeng Qi Zhaoguo Zheng Qiang Liu Source Type: research