Adverse Drug Reactions to Opioids: A Study in a National Pharmacovigilance Database

ConclusionPatients treated with opioids experienced ADRs, primarily nausea, dizziness, and vomiting. For those groups of drugs, no significant differences were found between the sexes, except for the vomiting associated with tramadol. In general, ADRs related to opioids presented higher RORs when uncorrected and corrected for sexes and expenditure than other drugs. There was more disproportionate reporting for ADRs concerning abuse, misuse, and medication errors for opioids than other drugs in the Dutch SRS.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research