Metformin alleviates adriamycin resistance of osteosarcoma by declining YY1 to inhibit MDR1 transcriptional activity

Chemotherapy resistance hinders the successful treatment of osteosarcoma (OS) to some extent. Previous studies have confirmed that metformin (Met) enhances apoptosis induced by chemotherapeutic drugs, but the ...

Source: BMC Clinical Pharmacology - October 12, 2023 Category: Drugs & Pharmacology Authors: Bowen Wu, Peng Li, Eryue Qiu and Jian Chen Tags: Research Source Type: research