Atorvastatin lowers 68Ga-DOTATATE uptake in coronary arteries, bone marrow and spleen in individuals with type 2 diabetes

Conclusions/interpretation68Ga-DOTATATE uptake across the cardio –haematopoietic axis was lower after statin therapy in individuals with type 2 diabetes. Therefore,68Ga-DOTATATE is promising as a metric for vascular and haematopoietic inflammation in intervention studies using anti-inflammatory therapeutics in individuals with type 2 diabetes.Trial registrationClinicalTrials.gov NCT05730634Graphical Abstract
Source: Diabetologia - Category: Endocrinology Source Type: research