Immune-scoring in head and neck squamous cell carcinoma: a scoping review

This study provides an overview of tumor-infiltrating immune cells and their prognostic significance, as well as a comparative summary of studies introducing an Immunoscore in HNSCC.EXPERT OPINION: With sufficient insight of the current literature, future studies could lead to the definition and validation of a new immune-based classification system for HNSCC. Such classification strategy could be a basis for patient selection and thus, optimize treatment outcomes and reduce unwanted complications. The heterogeneity of HNSCC subtypes as well as the intratumoral variability of immune infiltrates should be accounted for in the Immunoscore.PMID:37750738 | DOI:10.1080/1744666X.2023.2262140
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research