S100 Calcium-Binding Protein A8 Functions as a Tumor-Promoting Factor in Renal Cell Carcinoma via Activating NF- κB Signaling Pathway

CONCLUSION: Overall, S100A8 knockdown restrained RCC malignant biological properties, which was associated with the deactivation of the NF-κB signaling pathway. This present study demonstrates new insights that S100A8 may be a potential therapeutic target in RCC.PMID:37527815 | DOI:10.1080/08941939.2023.2241081

Source: Journal of Investigative Surgery - August 1, 2023 Category: Surgery Authors: Shu-Hui Wang Yan-Jie Xia Jing Yu Chun-Yan He Jie-Ru Han Ji-Xiang Bai Source Type: research