Portable Negative Pressure Wound Therapy Research Presents a Unique Perspective in Wound Care Management
J Invest Surg. 2021 Mar;34(3):344-345. doi: 10.1080/08941939.2019.1625986. Epub 2019 Jun 10.NO ABSTRACTPMID:33615962 | DOI:10.1080/08941939.2019.1625986 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - February 22, 2021 Category: Surgery Authors: Yanhan Ren Source Type: research

Our Surgeries Get Better, But Our Patients Get Worse
J Invest Surg. 2021 Mar;34(3):357-358. doi: 10.1080/08941939.2019.1642423. Epub 2019 Sep 25.NO ABSTRACTPMID:33615963 | DOI:10.1080/08941939.2019.1642423 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - February 22, 2021 Category: Surgery Authors: Roberto Seijas David Barastegui Ferran Monta ña Source Type: research

Crosslinked Polyethylene Demonstrates Substantially Improved Performance at Minimum 10-Year Follow-up Compared to Conventional Polyethylene
J Invest Surg. 2021 Mar;34(3):318-320. doi: 10.1080/08941939.2019.1621967. Epub 2019 Jun 4.NO ABSTRACTPMID:33615964 | DOI:10.1080/08941939.2019.1621967 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - February 22, 2021 Category: Surgery Authors: Robert H Hopper Source Type: research

Continuous Endotracheal Tube Cuff Pressure Control Decreases Incidence of Ventilator-Associated Pneumonia in Patients with Traumatic Brain Injury.
Authors: Sevdi MS, Demirgan S, Erkalp K, Akyol O, Ozcan FG, Guneyli HC, Tunali MC, Selcan A Abstract BACKGROUND: Ventilator-associated pneumonia (VAP) is a common cause of morbidity and mortality in intensive care unit (ICU), and among the several preventative strategies described to reduce the incidence of VAP, the most important is the endotracheal tube cuff (ETC) pressure. The present study was conducted on 60 patients who required mechanical ventilation (MV) in the ICU with traumatic brain injury (TBI). METHODS: The patients were randomized into two groups of 30, in which ETC pressure was regulated using a ...
Source: Journal of Investigative Surgery - February 16, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Betanin and Peripheral Artery Vasospasm.
Authors: Camps J, Iftimie S, Castro A, Joven J PMID: 33586585 [PubMed - in process] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - February 16, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Effect of an Information Video before Thyroid Biopsy on Patients Anxiety.
CONCLUSION: The video based information provided prior to thyroid biopsy draws the attention as an effective and easy to apply method to decrease the anxiety of the patients. PMID: 33557641 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - February 11, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

The Effectiveness of Caudal Block with Low Doses of Dexmedetomidine and Pethidine in Transrectal Prostate Biopsy: Preliminary Results.
CONCLUSION: The combination of dexmedetomidine and pethidine for CB in TRUS-Bx provided quality analgesia for the patient and prevented the development of postoperative urinary retention. PMID: 33550855 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - February 9, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Comparison of Patient Outcomes and Safety between Overlapping and Nonoverlapping Surgeries in Patients Undergoing Laparoscopic Common Bile Duct Exploration.
This study aimed to assess the clinical outcomes and safety of overlapping surgery during laparoscopic cholecystectomy and LCBDE for gallbladder and common bile duct stones (CBDS). MATERIAL AND METHODS: This study retrospectively reviewed 2736 laparoscopic cholecystectomy and LCBDE surgeries during 2013-2020. One thousand, two hundred eighty patients underwent LCBDE through cystic duct, including 867 receiving overlapping procedures, while 1456 underwent LCBDE through laparoscopic choledochotomy (LC), including 981 who underwent overlapping procedures. Data regarding patient sex, age, body mass index, the American Soci...
Source: Journal of Investigative Surgery - February 6, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Two Polyurethane Adhesives for PVDF Fixation Show Superior Biocompatibility in a Rat Model.
CONCLUSION: The developed polyurethane-based adhesives are a promising alternative with sufficient adhesive strength and superior short-term biocompatibility to cyanoacrylate. PMID: 33535001 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - February 5, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Prognostic Value and Molecular Mechanisms of Proteasome 26S Subunit, Non-ATPase Family Genes for Pancreatic Ductal Adenocarcinoma Patients after Pancreaticoduodenectomy.
Conclusion: GSEA revealed that PSMD6 and PSMD11 play a role in PDAC through various biological processes and signaling pathways, including TP53, CDKN2A, MYC pathway, DNA repair, KRAS, cell cycle checkpoint, NIK, NF-κB signaling pathway, and proteasomes. This study demonstrated that PSMD6 and PSMD11 could serve as a potential prognostic and diagnostic biomarkers for patients with early-stage PDAC after pancreaticoduodenectomy. PMID: 33525943 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - February 4, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Temporal Changes of Low Anterior Resection Syndrome Score after Sphincter Preservation: A Prospective Cohort Study on Repetitive Assessment of Rectal Cancer Patients.
Authors: Theodoropoulos GE, Liapi A, Spyropoulos BG, Kourkouni E, Frountzas M, Zografos G Abstract Background: There is a relative shortage of studies directly addressing the postoperative rectal cancer patients' evacuatory dysfunction, as estimated by the low anterior resection syndrome (LARS) score at repeated assessment time-points. The aim of the present study was to prospectively evaluate the incidence of LARS at predefined time intervals during the first 3 years after sphincter preserving rectal cancer surgery and to enlighten the effect of identified risk factors. Materials and methods: Seventy-eight ...
Source: Journal of Investigative Surgery - January 27, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Comparative Effectiveness and Safety of Anterior Cervical Corpectomy with Fusion, Laminoplasty, and Laminectomy and Instrumented Fusion for Ossification of the Posterior Longitudinal Ligament: A Systematic Review and Network Meta-Analysis.
CONCLUSIONS: Despite the higher probability of complications than LP, ACCF was the more recommended procedure for its highest ranking spectrums of JOA score improvement to treat the OPLL. PMID: 33472478 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 23, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Correction.
Authors: PMID: 33467975 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 22, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Ethanol and Radiofrequency Thyroid Ablation Move toward Mainstream Treatment for Benign Thyroid Nodules-Solitary or Combined Treatment, Neuromonitoring, and Shared Decision-Making?
Authors: Huang TY, Wu CW PMID: 33461350 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 20, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Early Detection of Intestinal Ischemia: The Sooner the Better.
Authors: Pietroletti R PMID: 33412977 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 10, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Sentinel Node Mapping at the Time of COVID-19 Outbreak.
Authors: Listorti C, Bogani G, Raspagliesi F, Folli S PMID: 33400886 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 7, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Comparison of Centrifugal and Pulsatile Perfusion to Preserve Donor Kidneys Using Ex Vivo Subnormothermic Perfusion.
Conclusion: In our porcine model with added warm ischemia simulating the effects of reperfusion after transplantation, pulsatile perfusion yielded similar renal protection compared with centrifugal perfusion kidney preservation. Both methods of perfusion can be used in ex vivo kidney perfusion systems. PMID: 33400888 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 7, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

The Learning Curve of Laparoendoscopic Single-Site Surgery in Benign Gynecological Diseases.
CONCLUSION: The learning curve of LESS for benign gynecological diseases indicates a stepwise process, during which the surgeon's CLS experience is the key, especially in ovarian cystectomy and myomectomy. For the training of young gynecologists, CLS should be emphasized in the early stage, and LESS should be introduced gradually. PMID: 33395538 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 6, 2021 Category: Surgery Tags: J Invest Surg Source Type: research

Continuous Jejunal Pouch and Residual Stomach Anastomosis Combined with Jejunal Lateral Anastomosis: An Improved Method of Gastrointestinal Reconstruction following Distal Gastrectomy.
Authors: Gong J, Wang B, Wang J, Li Y, Cao Y, Li W, Shang M, Huang L Abstract AIM: Currently, there is no optimal digestive tract reconstruction technique well recognized by scholars after distal gastrectomy. A new reconstruction method, which was modified from the classic Roux-en-Y procedure, the continuous jejunal pouch and residual stomach anastomosis combined with jejunal lateral anastomosis (Contin-L), was established. In order to fully clarify the superiority of this procedure, this study has conducted a systematic analysis and prepared a summary of the clinical data of patients who underwent distal gastrecto...
Source: Journal of Investigative Surgery - December 23, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Primary Angiosarcoma of the Gastrointestinal Tract: A Systematic Review of the Literature.
Authors: Schizas D, Mastoraki A, Giannakodimos I, Giannakodimos A, Ziogou A, Katsaros I, Frountzas M, Koutelidakis I, Vassiliu P, Pikoulis E Abstract Primary Gastrointestinal Angiosarcoma (PGAS) constitutes a rare malignant tumor arising from vascular or lymphatic endothelial cells. The aim of this study was to review the available literature on PGAS and to elucidate its biological behavior and optimal therapeutic approach. PubMed and Embase bibliographical databases were systematically searched (last search April 8th, 2020) for studies concerning PGAS. Ninety-eight studies met our inclusion criteria, involving 110...
Source: Journal of Investigative Surgery - December 23, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Molecular Nodal Restaging Based on CEACAM5, FGFR2b and PTPN11 Expression Adds No Relevant Clinical Information in Resected Non-Small Cell Lung Cancer.
Authors: Macia I, Aiza G, Ramos R, Escobar I, Rivas F, Ureña A, Aso S, Rosado G, Rodriguez-Taboada P, Deniz C, Nadal E, Capella G Abstract BACKGROUND: The relapse rate in non-small cell lung cancer (NSCLC) is high, even in localized disease, suggesting that the current approach to pathological staging is insufficiently sensitive to detect occult micrometastases present in resected lymph nodes. Therefore, we aimed to determine the prognostic value of the expression of embryonic molecular markers in histologically-negative lymph nodes of completely-resected NSCLC. METHODS: 76 completely-resected NSCLC pati...
Source: Journal of Investigative Surgery - December 23, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

The Clinical Utility of Autoantibodies in Patients with Idiopathic Granulomatous Mastitis.
CONCLUSION: Our findings did not support the clinical utility of autoantibodies including RF, ANA, anti-ds-DNA, pANCA and anti-CCP in IGM. PMID: 33327830 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 18, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Relationship between MTHFR Gene Polymorphisms and Gastrointestinal Tumors Development: Perspective from Eastern Part of Turkey.
CONCLUSION: The results showed that the A1298C polymorphism on the MTHFR gene can be a risk factor for gastric and esophageal cancer in eastern Turkey. These polymorphisms may have no effect on the life spans of the patients. PMID: 33322951 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 17, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

The Effects of Modified Lymphoscintigraphy Techniques on Sentinel Lymph Node Biopsy Success During the COVID-19 Pandemic Period.
CONCLUSIONS: In the present study, we believe that if technically possible, delayed images taken during the lymphoscintigraphy can assist the surgeon in terms of SLN detection and the number of SLNs removed. PMID: 33322956 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 17, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Concomitant Treatment of Ureteropelvic Junction Obstruction Complicated by Renal Calculi with Laparoscopic Pyeloplasty and Pyelolithotomy via 19.5F Rigid Nephroscope: A Report of 12 Cases.
CONCLUSION: LP and concomitant pyelolithotomy via 19.5 F rigid nephroscope is a safe and feasible option to treat UPJO with renal calculi, with acceptable success rate and stone-free rate. PMID: 33302748 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Is Autologous Fat Grafting an Oncologically Safe Procedure following Breast Conserving Surgery for Breast Cancer? A Comprehensive Review.
CONCLUSIONS: Our study lends further support to the notion that fat transfer after lumpectomy for breast cancer does not seem to increase the risk of LRR. However further prospective research is required in order to confirm this. PMID: 33302753 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Mini-Laparoscopy or Single-Site Robotic Surgery in Gynecology? Let's Think out of the Box.
Authors: Laganà AS, Garzon S, D'Alterio MN, Noventa M, Stabile G, Naem A, Ghezzi F PMID: 33302754 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Expression of CDK13 Was Associated with Prognosis and Expression of HIF-1 α and beclin1 in Breast Cancer Patients.
CONCLUSION: CDK13 was overexpressed in breast cancer tissues, and patients with higher CDK13 had poorer clinical outcomes. Further studies are still needed to reveal the clinical significance of CDK13 in breast cancer. PMID: 33292020 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 11, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Microwave Ablation of Visible Benign Thyroid Nodules with Different Internal Characteristics: A Comparative Study with Follow-up Results.
Authors: Mo HS, Wei L, Ye H, Li ZX Abstract PURPOSE: To investigate the effects of microwave ablation (MWA) on visible benign thyroid nodules (BTN) with different internal characteristics. MATERIALS & METHODS: A total of 51 cases with 53 visible BTN were treated by ultrasound-guided percutaneous MWA. The 53 nodules were classified into three categories according to the internal characteristics, which were simple solid, mainly solid and mainly cystic nodules. Ultrasound examinations were performed to evaluate the volume shrinkage rations during follow-up. The thyroid functions and the cervical cosmetic score...
Source: Journal of Investigative Surgery - December 11, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Vaginal Natural Orifice Transluminal Endoscopic Surgery (NOTES) for Treating Benign Adnexal Diseases: Past Results and Future Developments.
Authors: Evangelisti G, Barra F, Centurioni MG, D'Alessandro G, Alessandri F, Ferrero S PMID: 33289584 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 10, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Neoadjuvant Chemotherapy Followed by Radical Surgery versus Concurrent Chemo-Radiotherapy in the Treatment of Locally Advanced Cervical Cancer: A Multicenter Retrospective Analysis.
This study aims to evaluate oncological outcomes in women affected by locally advanced cervical cancer (LACC) treated by neoadjuvant chemotherapy before radical surgery (NACT + RS) or concurrent chemo-radiotherapy (CCRT). METHODS: This was a multicenter retrospective analysis of data related to women with LACC (FIGO stage IB2-IVA), who were treated by NACT + RS or CCRT between November 2006 and January 2018. The first endpoints were the evaluation of disease-free survival (DFS) and overall survival (OS); univariate and multivariate analyses were performed for identifying the prognostic facto...
Source: Journal of Investigative Surgery - December 10, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Influence of Modic Changes on Cage Subsidence and Intervertebral Fusion after Single-Level Anterior Cervical Corpectomy and Fusion.
This study enrolled 61 patients with MCs who underwent single-level ACCF between January 2010 and December 2015 at our institution. The control group included 63 age-matched patients without MCs treated during the same period. The results from clinical and radiological assessments were reviewed, and radiographic CS was defined by an intervertebral height at the final follow-up that was less than the postoperative intervertebral height. RESULTS: No significant differences in gender, age, operative time, blood loss, or follow-up results were observed between the MCs and control groups. Significantly more patients experie...
Source: Journal of Investigative Surgery - December 8, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Surgical Treatment of Cervicothoracic Junction Lesions in Children: A Series of 18 Cases.
CONCLUSIONS: The lesions at the cervicothoracic junction (C7-T4) in children may be managed with the simple LACA used in most patients. For malignancies extending to the T4 level, LACA and VATS could be performed in combination to resect lesions completely and invasively. PMID: 33283571 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 8, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Posture Dependent Hypoxia Following Lobectomy: The Achilles Tendon of the Lung Surgeon?
CONCLUSIONS: Platypnoea-Orthodeoxia Syndrome after lobectomy is a rare cause of post-operative dyspnea/hypoxia. It is the result of right-to-left shunt via an interatrial communication. Mediastinal relocation, stretching of the atrial septum and aortic root dilatation are among the functional elements necessary for the Platypnoea-Orthodeoxia Syndrome manifestation. PMID: 33263463 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 4, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Serum Albumin in Patients Affected by Gynecological Cancers: Can It Have a Future Role in Prognostic Index or Nomogram?
Authors: Barra F, Alessandri F, Evangelisti G, Centurioni MG, Ferrero S PMID: 33267622 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 4, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Quality of Life Improves Following Laparoscopic Hemifundoplication in Neurologically Non-Impaired Children with Gastroesophageal Reflux Disease: A Propensity Score-Matched Analysis.
Authors: Frongia G, Weitz D, Bauer J, Probst P, Steffens F, Pfisterer D, Mehrabi A, Günther P Abstract BACKGROUND: Quality of life (QOL) data following pediatric fundoplication for gastroesophageal reflux disease (GERD) are rare. Present study assessed the QOL in neurologically non-impaired children before and after laparoscopic hemifundoplication (LHF) in comparison to healthy controls. METHODS: PedsQL™ questionnaires assessed data on gastrointestinal symptoms (GIS) and general well-being (GWB) were compared in a propensity score-matched analysis (60 patients' pairs for time-point of surgery and 51 ...
Source: Journal of Investigative Surgery - December 1, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Technical Pearls When Raising the Latissimus Dorsi Flap and Inducing Ischemia in Swine.
Authors: Naparus A PMID: 33251916 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 1, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

The Association of Chronic Opioid Use with Resource Utilization and Outcomes after Emergency General Surgery.
Authors: Oliver JB, Iyer UR, Merchant AM Abstract INTRODUCTION: Chronic opioid use is prevalent among patients undergoing emergent surgery. We sought to understand it on the outcomes of the most common emergency surgery procedures, Appendectomy and Cholecystectomy. METHODS: We used the National Inpatient Sample to identify chronic opioid use in emergency appendectomies (n = 953) and cholecystectomies (n = 2826) from 2005 to 2014. Primary outcome was length of stay (LOS), and secondary outcomes included total charges and mortality. LOS was analyzed with multivariate Poisson regression...
Source: Journal of Investigative Surgery - November 27, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Esthetics Effect and the Modified Placement of Robotic-Assisted Single-Site Laparoscopic Gynecologic Surgery by Common Robotic Instruments and LAGIS Single-Site Port.
Authors: Liu X, Gao J, Wang J, You J, Chu J, Jin Z Abstract OBJECTIVES: To investigate the bio-functions and the molecular mechanisms of NIN1/proteasome 26S subunit non-ATPase 8 binding protein 1 homolog (NOB1) in colorectal cancer cells. METHODS: NOB1 expression was silenced using si-RNA in SW480 and LoVo cells. The transfection efficiency was measured by western blotting and RT-qPCR. Subsequently, the proliferation of SW480 and LoVo cells was determined using both MTT assay and colony-formation assay. Apoptosis and cell cycle analysis were determined using flow cytometry. RESULTS: Compared with the normal...
Source: Journal of Investigative Surgery - November 26, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Improved Arterial Preservation achieved by Combined Use of Indocyanine Green Angiography and Doppler Detector during Microsurgical Subinguinal Varicocelectomy.
Authors: Cho CL PMID: 33222577 [PubMed - in process] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 24, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Oversewing the Staple Line. It Is Really Necessary?
Authors: Trindade EN, Leite C, Trindade MRM PMID: 33207967 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 21, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

The Transition from Experimental Data to Clinical Practice Using P4HB Mesh in Ventral Hernia Repair.
Authors: Berrevoet F PMID: 33207987 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 21, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Regenerated Cell Therapy for Stress Urinary Incontinence: A Meta-Analysis.
CONCLUSIONS: Limited studies have indicated the safety and effectiveness of regenerated cells for treating stress UI in the follow-up period, which may be an ideal method to treat stress UI in the future. Moreover, nucleated cells with platelets and myocytes with fibroblasts were markedly effective, but whether cell injection therapies elicit superior effects need further confirmation. PMID: 33198535 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 18, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

The Diagnostic Value of ischemia-modified albumin (IMA) and signal peptide-CUB-EGF domain-containing protein-1 (SCUBE-1)  in an Experimental Model of Strangulated Mechanical Bowel Obstruction.
CONCLUSION: The study findings showed that both IMA and SCUBE-1 values increased in a strangulated MBO model in rats. We think that IMA and SCUBE-1 values can be used as a markers of damage in the early period in strangulated MBO, and that the patient's surgery requirement can thus be determined in the early period. PMID: 33190564 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 17, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Stop Calling Me Cavernous Hemangioma! A Literature Review on Misdiagnosed Bony Vascular Anomalies.
Authors: Liberale C, Rozell-Shannon L, Moneghini L, Stavros T, Giacomo C, Nocini R Abstract Vascular malformations of the bone most often involve the cranio-facial area. Even in relevant peer reviewed journals, venous malformations are often misdiagnosed as "hemangiomas" or "angiomas" of the bone. By reviewing literature from the past 5 years (2013-2018), we found many reports of vascular malformations of the bone where the diagnosis was incorrect. Unfortunately, there is still much confusion in understanding and/or diagnosing vascular malformations, despite the fact that in recent years many pa...
Source: Journal of Investigative Surgery - November 11, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Treatment of Thoracic Ossification of Posterior Longitudinal Ligament with One-Stage 360 Degree Circumferential Decompression Assisted by Piezosurgery.
CONCLUSIONS: The use of piezosurgery can safely and effectively complete one-stage simple posterior TOPLL with 360-degree circular decompression. The incidence of complications is not high, and a good outcome can be obtained. PMID: 33164598 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 11, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Afterthoughts from an Unexpected Morbidity under COVID-19 pandemic.
Authors: Navarro F, Jarry C, Gabrielli M PMID: 33164621 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 11, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Simultaneous Side-by-Side Bilateral Placement of Braided-Type Metal Stents Using a 5.9F Delivery System for Unresectable Malignant Hilar Biliary Obstruction: A Preliminary Feasibility Study.
CONCLUSIONS: Simultaneous SBS stent placement using novel braided metal stents was found to be feasible in patients with MHBO. Prospective well-designed clinical studies are needed to certify the efficacy of the stenting technique for MHBO. PMID: 33148060 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 7, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

COL11A1 Was Involved in Cell Proliferation, Apoptosis and Migration in Non-Small Cell Lung Cancer Cells.
Authors: Tu H, Li J, Lin L, Wang L Abstract BACKGROUND: Type XI collagen (COL11A1) was reported to associate with malignancy in several cancer types, whereas its role in lung cancer is not fully understood. Therefore, the present study aimed to explore the expression level and biological role of COL11A1 in lung cancer cells. METHODS: Gene Expression Omnibus (GEO) database containing 6 lung cancer tissues and normal lung tissues was used to identify potential aberrantly expressed genes. The expression of COL11A1, apoptosis related genes, cell cycle related genes and migration associated genes at the protein leve...
Source: Journal of Investigative Surgery - November 7, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Letter to the Editor regarding the Article "Polyvinylidene Fluoride Mesh Use in Laparoscopic Ventral Mesh Rectopexy in Patients with Obstructive Defecation Syndrome for the First Time" by Alemrajabi et  al.
Letter to the Editor regarding the Article "Polyvinylidene Fluoride Mesh Use in Laparoscopic Ventral Mesh Rectopexy in Patients with Obstructive Defecation Syndrome for the First Time" by Alemrajabi et al. J Invest Surg. 2020 Nov 05;:1 Authors: Dievernich A PMID: 33150800 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - November 7, 2020 Category: Surgery Tags: J Invest Surg Source Type: research