Effects of Bone-Plate Material on the Predicted Stresses in the Tibial Shaft Comminuted Fractures: A Finite Element Analysis.
CONCLUSIONS: CF50 plates can be safely used in the tibial shaft comminuted fracture. The micromotion in the CF50 and CF60 plate was more beneficial to callus formation and fracture healing. The stress shielding of the cortex bone under the CF50 plate was the lowest. The finite element analysis indicated that the CF-PEEK material is worthy of further study because of its biomechanical advantages. PMID: 33089722 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 24, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Correction.
Authors: PMID: 33076726 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 22, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Systemic Amelioration via Curcumin in Rats following Splenectomy: Lipid Profile, Endothelial and Oxidative Damage.
Authors: Altinel Y, Kose E, Karacaglar A, Demirgan S, Sozer V, Ozkaya G, Gulcicek OB, Simsek G, Uzun H Abstract BACKGROUND: We investigated the postsurgical effects of splenectomy with additional curcumin therapy, as an antioxidant, anti-inflammatory substance among the lipid profile and histopathological changes. MATERIALS AND METHODS: 32 rats were randomly divided into four groups: control group (L): laparotomy, sham group: splenectomy (S), splenectomy group treated with curcumin (SC) and splenectomy group treated with corn oil (SCO) for 28 days. The primary outcomes; total cholesterol (TC), triglyceri...
Source: Journal of Investigative Surgery - October 22, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Isthmocele: When Surgery Is Both the Problem and the Solution.
Authors: Laganà AS, Garzon S, Alkatout I, Hortu İ, Gitas G, Vitale SG, Gubbini G PMID: 33078642 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 22, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Correction.
Authors: PMID: 33081561 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 22, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

The Impact of C-Reactive Protein to Albumin Ratio on 1-Year Mortality after Discharge.
Authors: Higashikawa T, Shigemoto K, Usuda D, Okuro M, Sawaguchi T PMID: 33084467 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 22, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Bacteria Associated with Granulomatous Lobular Mastitis and the Potential for Personalized Therapy.
Authors: Li XQ, Wu HL, Yuan JP, Liu TG, Sun SR, Chen C Abstract Granulomatous lobular mastitis (GLM), also known as idiopathic granulomatous mastitis (IGM), is a chronic inflammatory lesion of the breast. The incidence of GLM has been increasing in recent years, especially among young women. The etiologies of GLM have not been fully elucidated but are associated with autoimmunity and bacterial infection. Bacteria, especially Corynebacterium species, play important roles in GLM. In this article, we review research progress regarding the bacteriology of GLM attained with the application of several new high-throughput...
Source: Journal of Investigative Surgery - October 21, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Comparison of the Efficacy of Two Laparoscopic Surgical Procedures Combined with Hysteroscopic Incision in the Treatment of Cesarean Scar Diverticulum.
CONCLUSION: As two new surgical methods that preserve uterine integrity, the laparoscopic "muscle flap filling suture method" and "folding suture method" combined with hysteroscopic incision are safe and effective treatments for repairing CSD. PMID: 33059509 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 21, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

A Reply to the Comment to: "Polyvinylidene Fluoride Mesh Use in Laparoscopic Ventral Mesh Rectopexy in Patients with Obstructive Defecation Syndrome for the First Time".
A Reply to the Comment to: "Polyvinylidene Fluoride Mesh Use in Laparoscopic Ventral Mesh Rectopexy in Patients with Obstructive Defecation Syndrome for the First Time". J Invest Surg. 2020 Oct 12;:1 Authors: Alemrajabi M, Moradi M, Darabi B PMID: 33043727 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 14, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Mechanical and Histological Characteristics of Phasix ™ ST Mesh in a Porcine Model of Hernia Repair.
The objective of this study was to determine mechanical and histological properties of Phasix™ ST Mesh in various defect sizes and characterize the tissue replacing Phasix™ ST Mesh in a porcine model of ventral hernia repair. METHODS: Simulated hernia defects were surgically created in the midline of twenty-four (n = 24) Yucatan pigs. Treatment groups included 8 cm defect sutured closed (buttress) and unclosed 4 cm and 8 cm defect groups. Phasix™ ST Mesh (15 cm diameter circle) was implanted laparoscopically and fixated circumferentially with SorbaFix™ A...
Source: Journal of Investigative Surgery - October 14, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Primary Squamous Cell Carcinoma of Colon and Rectum: A Systematic Review of the Literature.
Conclusions: Colorectal Squamous Cell Carcinoma is a rare tumor with an aggressive behavior. Surgery is the standard of treatment for the colontumors, while the role of chemoradiotherapy is promising especially for rectal tumors. Further clinical trials are necessary to determine the preferred treatment approach. PMID: 33021125 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 8, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Is Claudin 4 a Player to Be Reckoned with or Not in the Context of Lung Transplantation?
Authors: Niroomand A, Lindstedt S PMID: 33021126 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 8, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Serum Albumin as a Predictor of Survival after Interval Debulking Surgery for Advanced Ovarian Cancer (AOC): A Retrospective Study.
CONCLUSION: Hypoalbuminaemia at diagnosis is a poor prognostic factor in AOC. Normalization of serum albumin after NACT is a potential predictor of survival. PMID: 33021127 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 8, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Use of Prostate Systematic and Targeted Biopsy on the Basis of Bi-Parametric Magnetic Resonance Imaging in Biopsy-Na ïve Patients.
CONCLUSIONS: No significant difference was found in the detection of CSPC between TB and SB; however, both techniques revealed substantial added value and combination of TB and SB could further improve this detection rate without increasing the detection of CIPC. PMID: 32996795 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 2, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

LAW Trial - The Impact of Local Anesthetics Infiltration in Surgical Wound for Gastrointestinal Procedures (LAW): A Double-Blind, Randomized Controlled Trial.
CONCLUSIONS: There is no clear association between bupivacaine infiltration and reduction of SSI rate according to our study. Wound bupivacaine infiltration is associated with a lower dose of epidural infusion and opioid requirements. PMID: 32996796 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 2, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Emergency General Surgery: Let's Get It Right from the Beginning!
Authors: Tsoulfas G PMID: 32996807 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 2, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Higher Rate of Postoperative Complications in Delayed Achilles Tendon Repair Compared to Early Achilles Tendon Repair: A Meta-Analysis.
CONCLUSION: Our study showed delayed repair could obtain similar functional outcomes and subjective assessment when compared with acute repair. However, the rate of complications after delayed repair was higher than that of early repair. Further high-quality randomized controlled trials (RCT) are needed to evaluate the difference. PMID: 32990099 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - October 1, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Full-Dress Rehearsals with Actual Non-Infected Patients Builds Confidence and Familiarity - An Experience from Singapore during the COVID-19 Pandemic.
CONCLUSIONS: Simulation training with patients provides participants with a level of realism that is critical for rapid learning. In crisis management, the most effective protocol familiarization is important to instill confidence in the PPE, workflows and healthcare partners. PMID: 32969721 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 26, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

5% Lidocaine Hydrochloride Cream for Wound Pain Relief: A Multicentre Observational Study.
Authors: Janowska A, Papa G, Romanelli M, Davini G, Oranges T, Stocco C, Arnez ZM, Dini V Abstract BACKGROUND: Lidocaine hydrochloride is frequently used for management of painful wounds. This prospective, multicentre study examined the effects of 5% lidocaine cream on wound pain relief. MATERIAL AND METHODS: The study included 78 patients with painful wounds treated with 5% Lidocaine cream for two weeks in two Italian Hospitals. Patients' perception of pain was recorded by, using the 5-point Visual Rate Scale and the 11-point Numerical Pain Rating Scale. All medications and adverse events were evaluated in a d...
Source: Journal of Investigative Surgery - September 26, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Cuff Anastomosis of Both Renal Artery and Vein to Minimize Thrombosis: A Novel Method of Kidney Transplantation in Mice.
CONCLUSION: In summary, cuff anastomosis can be used to eliminate thrombosis formation in the mouse model of kidney transplantation. PMID: 32965132 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 25, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Doing More with Less: Surgical Training in the COVID-19 Era.
CONCLUSIONS: The "new" era forced the educational boards to reexamine training curriculums. Innovation strategies and cooperation on the part of surgical residency programs is crucial. Strong leadership is needed, on the part of the education bodies with restructuring of the surgical programmes to accommodate alternative ways of training is necessary to maintain rigorous standards of education and training. PMID: 32959688 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 23, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Inheritance, Environment and Genesis of Inguinal Hernias.
Authors: Sandblom G PMID: 32959691 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 23, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Sublabial Approach to Tip Rhinoplasty: A Cadaver Model.
CONCLUSIONS: Several rhinoplasty techniques can be successfully performed on cadavers via the sublabial approach and we hope this work can be translated to human subjects. PMID: 32959698 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 23, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Can Rodent Model of Acetic Acid-Induced Colitis be Used to Study the Pathogenesis of Colitis-Associated Intestinal Fibrosis?
Authors: Subramanian S, Du C, Tan XD PMID: 32951484 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 22, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Improving Animal Model of Induced Colitis by Acetic Acid in Terms of Fibrosis and Inflammation Incidence in the Colon.
CONCLUSION: Our results showed that the evaluation of the disease process from 3 days to nine days after a 10 min contact of acid to the colon is a suitable model that mimics the histological features of the disease. PMID: 32945217 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 21, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Evaluation of the Hemostatic Efficacy of Two Powdered Topical Absorbable Hemostats Using a Porcine Liver Abrasion Model of Mild to Moderate Bleeding.
Authors: MacDonald MH, Tasse L, Wang D, Zhang G, De Leon H, Kocharian R Abstract INTRODUCTION: Topical hemostatic agents, used alone or in combination, have become common adjuncts to manage tissue and organ bleeding resulting from trauma and surgical procedures. Oxidized regenerated cellulose (ORC) is one of the most commonly used adjunctive hemostatic agents. The aim of the present study was to compare the hemostatic efficacy of a novel ORC-based product, SURGICEL® Powder Absorbable Hemostat (Surgicel-P) to that of HEMOBLAST™ Bellows (Hemoblast-B), a collagen-based combination powder. METHODS: Using ...
Source: Journal of Investigative Surgery - September 18, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

The Effectiveness of Jet (Needle-Free) Injector to Provide Anesthesia in Child Circumcision under Local Anesthesia.
CONCLUSION: Our study showed that anesthesia using a jet injector can not provide sufficient analgesia so as to comfortably complete circumcision in pediatric circumcisions performed under local anesthesia. PMID: 32900257 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 11, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Expression of Claudin-4 in Lung Ischemia-Reperfusion Injury in Experimental Lung Transplantation.
CONCLUSION: CLDN4 expressed in BALF and the pulmonary tissue during the first 5 h within 72 h of the PGD window are not associated by the deterioration of lung function, edema and lung histological injury, in LTx with CIT 50 min or 6 h, CLDN4 does not seem to be a valuable indicator of LIRI. PMID: 32900258 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 11, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Are We Ready for an Optimal Neuromuscular Block Management for Neural Monitoring during Thyroid Surgery?
Authors: Vilallonga R PMID: 32892664 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 9, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Apoptosis and Autophagy in the Pathogenesis of Osteoarthritis.
Authors: Castrogiovanni P, Ravalli S, Musumeci G PMID: 32885706 [PubMed - in process] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 6, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Analysis of Myomectomy during Cesarean Section: A Tertiary Center Experience.
CONCLUSION: Myomectomy during CS is safe and can be applied regardless of the location, size, type, and number of myomas. However, to make myomectomy routine during CS, multi-center studies that include more cases are needed. PMID: 32865048 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 2, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Comparison of Image-Guided Iodine-125 Seed Interstitial Brachytherapy and Local Chemotherapy Perfusion in Treatment of Advanced Pancreatic Cancer.
CONCLUSION: Iodine-125 seed interstitial brachytherapy could achieve better efficacy with no increased side complications than chemotherapy perfusion in advanced pancreatic cancer. PMID: 32865062 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 2, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Does Unplanned Soft Tissue Sarcoma Surgery Have a Negative Effect on Prognosis?
CONCLUSION: Patients undergoing re-excision after an inappropriate resection and undergoing planned resection had a similar prognosis. Superficial, upper extremity-localized, and relatively small-size tumors are more prone to inadequate surgical resection. MRI can be used to detect residual tumors at a high rate in patients who have undergone unplanned surgery. Distant organ metastasis is the most important factor affecting survival. PMID: 32862737 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - September 1, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Papaverine Has Therapeutic Potential for Sepsis-Induced Neuropathy in Rats, Possibly via the Modulation of HMGB1-RAGE Axis and Its Antioxidant Prosperities.
CONCLUSION: Papaverine demonstrates neuroprotective effects in a rat model of SCIN. Considering its anti-inflammatory and antioxidant properties, papaverine's neuroprotective effects possibly stem from the suppression of the RAGE-HMGB1 axis. PMID: 32842806 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 29, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Development and Validation of Prognostic Nomograms to Predict Overall and Cancer-Specific Survival for Patients with Adenocarcinoma of the Urinary Bladder: A Population-Based Study.
CONCLUSION: Our study constructed and validated nomograms with improved discriminative abilities and clinical benefits to predict the survival outcomes of ACB patients. The models might assist clinicians in optimizing therapeutic management on individual levels. PMID: 32851885 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 29, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Sleeve Gastrectomy Surgery Improves Glucose Metabolism by Downregulating the Intestinal Expression of Sodium-Glucose Cotransporter-3.
CONCLUSION: The results suggest that reducing SGLT3 expression might contribute to lowering blood glucose and controlling body weight after SG. PMID: 32835540 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 26, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Correction.
Authors: PMID: 32814484 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 22, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

ABC of Surgical Teaching: Time to Consider a Global Blueprint for Holistic Education.
CONCLUSIONS: This proof of concept, "Omnigon iG4," proposes an adaptable version of a curriculum blueprint. The framework allows educators to establish a surgical curriculum with the ability to map out competencies, permitting full control over their intended learning outcomes. This can form the basis for developing globally adaptable multifaceted Simulation-Based learning (SBL) courses or even surgical curricula for undergraduates. PMID: 32806964 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 20, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Procalcitonin Measurement in Pleural Fluid to Predict Infectious Complications of the Chest Post Lung Resection.
This study investigated whether PCT level in pleural fluids could predict the infectious complications in the chests of patients undergoing lobectomy. PATIENTS AND METHODS: Thirty-four patients undergoing lobectomy for lung cancer were enrolled. PCT levels were measured in serum (S-PCT) and pleural effusion (PF-PCT) on consecutive postoperative days (PODs). The patients were grouped according to the development of chest infectious complications (atelectasis/pneumonia, postoperative infected pleural effusion/empyema/infected space, prolonged air leak>5 days with evidence of infection, lung torsion, and lung in...
Source: Journal of Investigative Surgery - August 20, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

An Update in Reconstructive Surgery.
Authors: Alfotawi R PMID: 32799704 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 19, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

NGF/TrKA Signaling Pathway and Atrial Fibrillation: Is There a Link?
Authors: Ammannaya GKK PMID: 32799710 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 19, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Factors Contributing to Extended Hospital Length of Stay in Emergency General Surgery †.
CONCLUSIONS: Several factors are independently associated with extended LOS for those undergoing the most common EGS procedures. Five of these were associated with an increased LOS for all four procedures. These included, age (61+), hypertension, sepsis, cancer, and Black race. PMID: 32791866 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 16, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Precision Neuromuscular Block Management for Neural Monitoring During Thyroid Surgery.
Authors: Lu IC, Wu SH, Chang PY, Ho PY, Huang TY, Lin YC, Kamani D, Randolph GW, Dionigi G, Chiang FY, Wu CW Abstract INTRODUCTION: Titration of neuromuscular block (NMB) plays a key role in intraoperative recurrent laryngeal nerve monitoring during thyroid surgery. The combination of neuromuscular blocking agent and timely partial reversal of NMB was investigated in both animal experiments and clinical neuro-monitored thyroidectomy. METHODS: In animal experiments, 8 piglets received sugammadex to assess the laryngeal EMG recovery after rocuronium-induced NMB. In clinical monitored thyroidectomy, 40 patients ea...
Source: Journal of Investigative Surgery - August 16, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Anisotropic Polytetrafluoroethylene Cardiovascular Conduits Spontaneously Expand in a Growing Lamb Model.
CONCLUSIONS: Anisotropic ePTFE conduits can be safely implanted in growing lambs with stable hemodynamics. This spontaneously expanding anisotropic conduit may represent a novel approach to congenital heart repairs that would avoid the need for reoperation or multiple operations. PMID: 32791879 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 16, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Is Lanreotide Really Useful in High Output Stoma? Comparison between Lanreotide to Conventional Antidiarrheal Treatment Alone.
CONCLUSION: The trial was prematurely stopped due to the low number of patients included. The question of the usefulness of somatostatin analogues in HOS persists, especially as the cost of this treatment is high, and there is a lack of evidence of its effectiveness. PMID: 32746647 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Latissimus Dorsi Myocutaneous Flap Procedure in a Swine Model.
CONCLUSION: We have identified and described a pre-clinical large animal flap model that can be easily reproduced for translational studies of multiple scientific areas including flap-based repair, ischemia, ischemia reperfusion, and operative technique. This provides an important model for ready replication in preclinical studies of many varieties. PMID: 32752901 [PubMed - as supplied by publisher] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Effects of Trans-Cinnamaldehyde on Reperfused Ischemic Skeletal Muscle and the Relationship to Laminin.
This study is designed to investigate the effects of trans-cinnamaldehyde (TCA), a volatile oil of cinnamon structure, on the contractile dysfunction due to I-R injury of rat extensor-digitorum-longus (EDL) muscle. MATERIALS AND METHODS: Sprague-Dawley rats were randomly divided into three groups. Except for the animals in the control group, all animals received saline (3-ml/kg) or TCA solution (30-mg/kg) which was administered orally three times with an 8-h interval before ischemia. After 24-hours, experimental groups were subjected to 3-h of lower extremity ischemia followed by 5-h reperfusion period. Then, the compo...
Source: Journal of Investigative Surgery - August 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Pre-, Peri-, and Postoperative Intravenous Ropivacaine versus that of Lidocaine for Analgesia after Hand-Assisted Laparoscopic Surgery of Left Colon Cancer: A Retrospective Analysis.
The objectives of the study were to evaluate the effectiveness of pre-, peri-, and postoperative intravenous ropivacaine against that of lidocaine on the postoperative pain, bowel function recoveries, and hospital stays in patients who underwent surgery of left colon cancer. MATERIALS AND METHODS: Data regarding total doses of fentanyl required, bowel function recoveries, surgical-related complications, and hospital stays of 367 patients who underwent hand-assisted laparoscopic surgery of left colon cancer were retrospectively collected and analyzed. Patients received pre-, peri-, and postoperative intravenous normal s...
Source: Journal of Investigative Surgery - August 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Detection of False Negative Sentinel Lymph Node in Cutaneous Oncology: A General Reappraisal.
Authors: Paolino G PMID: 32772780 [PubMed - in process] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research

Correction.
Authors: PMID: 32772781 [PubMed] (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - August 13, 2020 Category: Surgery Tags: J Invest Surg Source Type: research