Survival and Prognosis for Patients with Rectal Melanomas in the United States: A SEER-Based Study
CONCLUSION: Clinicopathologic relevance with tumor prognosis was confirmed in this study. Our nomogram can provide a relatively accurate prediction of the survival rate of patients with RM.PMID:38234036 | DOI:10.1080/08941939.2024.2302564 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 18, 2024 Category: Surgery Authors: Fan Zhang Boqi Xu Yao Peng Runda Wu Shan Tong Zhongqi Mao Source Type: research

The HIF-1 α/PKM2 Feedback Loop in Relation to EGFR Mutational Status in Lung Adenocarcinoma
CONCLUSION: Different expression and clinical features of HIF-1α/PKM2 feedback loop was existed between LUAD and normal lung tissues, especially in EGFR mutational tumors, supporting the relationship between EGFR mutation and the key related proteins of aerobic glycolysis (HIF-1α and PKM2) in lung adenocarcinomas.PMID:38224012 | DOI:10.1080/08941939.2023.2301081 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 15, 2024 Category: Surgery Authors: Yuan Wang Hongguang Lian Jiajun Li Man Zhao Zengfang Hao Xue Zheng Linyuan Zhao Jinfeng Cui Source Type: research

Anterior, Posterior and Anterior-Posterior Approaches for the Treatment of Thoracolumbar Burst Fractures: A Network Meta-Analysis of Randomized Controlled Trials
CONCLUSION: All three approaches were safe approaches with advantages and disadvantages. The selection of surgical approaches for the treatment of thoracolumbar burst fractures may be individualized.PMID:38199978 | DOI:10.1080/08941939.2024.2301794 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - January 10, 2024 Category: Surgery Authors: Yuchen Duan Dagang Feng Jun Chen Yamei Wu Tong Li Leiming Jiang Yong Huang Source Type: research

Effects of Mesalamine Combined with Live Combined Bifidobacterium, Lactobacillus and Enterococcus Capsules on Intestinal Mucosa Barrier Function and Intestinal Microbiota in Mildly Active Crohn's Disease Patients
Conclusion: Mesalamine combined with Live combined Bifidobacterium, Lactobacillus and Enterococcus capsules are more effective in treating mildly active Crohn's disease.PMID:38159563 | DOI:10.1080/08941939.2023.2297565 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 30, 2023 Category: Surgery Authors: Meiqin Shen Yingqi Shi Zhenming Ge Junbo Qian Source Type: research

Association of miR-203 Expression with Prognostic Value in Patients with Esophageal Cancer: A Systematic Review and Meta-Analysis
CONCLUSION: The expression of miR-203 is significantly correlated with the prognostic value in patients with esophageal cancer. Esophageal cancer patients with high expression of miR-203 had better prognosis than those with low expression of miR-203. Due to the limited studies included in this meta-analysis, more trials are needed to confirm the conclusions of this study in the future.PMID:38047456 | DOI:10.1080/08941939.2023.2285780 (Source: Journal of Investigative Surgery)
Source: Journal of Investigative Surgery - December 4, 2023 Category: Surgery Authors: Qirun Cheng Lipeng Chen Liping Ni Source Type: research