CAB39 promotes cisplatin resistance in bladder cancer via the LKB1-AMPK-LC3 pathway

In conclusion, our study shows that CAB39 counteracts the killing of cisplatin by enhancing the autophagy of BC cells to damaged mitochondria and other organelles to alleviate the damage of cells caused by harmful substances such as ROS.PMID:37726090 | DOI:10.1016/j.freeradbiomed.2023.09.017

Source: Free Radical Biology and Medicine - September 19, 2023 Category: Biology Authors: Dongyang Gao Runchang Wang Yuwen Gong Xiaoquan Yu Niu Qian Enguang Yang Guangrui Fan Junhai Ma Chaohu Chen Yan Tao Jianzhong Lu Zhiping Wang Source Type: research