Transdiagnostic risk of mental disorders in offspring of affected parents: a meta-analysis of family high-risk and registry studies

This study demonstrates at a global, meta-analytic level that offspring of affected parents have strongly elevated RR and lifetime risk of developing any mental disorder as well as the same mental disorder diagnosed in the parent. The transdiagnostic risks suggest that offspring of parents with a range of mental disorders should be considered as candidates for targeted primary prevention.PMID:37713573 | PMC:PMC10503921 | DOI:10.1002/wps.21147

Source: World Psychiatry - September 15, 2023 Category: Psychiatry Authors: Rudolf Uher Barbara Pavlova Joaquim Radua Umberto Provenzani Sara Najafi Lydia Fortea Maria Ortu ño Anna Nazarova Nader Perroud Lena Palaniyappan Katharina Domschke Samuele Cortese Paul D Arnold Jehannine C Austin Michael M Vanyukov Myrna M Weissman Alla Source Type: research