Single-cell communication patterns and their intracellular information flow in synovial fibroblastic osteoarthritis and rheumatoid arthritis

CONCLUSION: Increased understanding of the interaction networks between synovial fibroblast subtypes, particularly the shared and unique cellular communication features between osteoarthritis and rheumatoid arthritis and their hub cells, should help inform the design of therapeutic agents for inflammatory joint disease.PMID:37704178 | DOI:10.1016/j.imlet.2023.09.005

Source: Immunology Letters - September 13, 2023 Category: Allergy & Immunology Authors: Jiajian Wang Caihong Liu Tingting Wang Sidi Li Yunmeng Bai Fulin Pan Jiayi Wang Jing Han Ruibin Luo Xing Wan Haiyan Cui Yingcai Huang Mingqi Zheng Xiaoping Hong Jian V Zhang Ruihuan Xu Source Type: research