Single-cell analysis of the miRNA activities in tuberculous meningitis (TBM) model mice injected with the BCG vaccine

CONCLUSION: In our study, an in-depth exploration of the mRNA expression and miRNA activity of macrophages, microglia, epididymal cells, neurons and vascular smooth muscle cells during TBM progression was conducted using scRNA-Seq, which provided novel insights into the immune cell engagement in TBM patients.PMID:37708706 | DOI:10.1016/j.intimp.2023.110871

Source: International Immunopharmacology - September 14, 2023 Category: Allergy & Immunology Authors: Xiaolin Zhang Lei Pan Peng Zhang Lei Wang Yidan Shen Ping Xu Yang Ren Wei Huang Ping Liu Qingguo Wu Feng Li Source Type: research