Activation of the DNA damage response pathway in the infected gastric tissue with Helicobacter pylori: a case-control study

Conclusions: Our results provide new data that may support the potential involvement ofH. pylori infection in the activation of genes involved in DNA damage response, mainly through a non-homologous end-joining DNA repair system that might be linked to mutagenesis in the pre-cancerous gastric tissue.

Source: The Journal of Infection in Developing Countries - August 30, 2023 Category: Infectious Diseases Authors: Amiratabak Rajaei, Armin Ghameshlou, Reza Shirkoohi, Abbas Shakoori Farahani, Seyedeh Zohre Mirbagheri, Ronak Bakhtiari, Melika Sadat Haeri, Ali Rashidi-Nezhad, Masoud Alebouyeh Source Type: research