Upregulation of hypothalamic TRPV4 via S100a4/AMPK α signaling pathway promotes the development of diet-induced obesity

This study provides evidence that hypothalamic TRPV4 plays a significant role in regulating homeostasis. Hypothalamic TRPV4 emerges as a target for therapeutic intervention against obesity.PMID:37683711 | DOI:10.1016/j.bbadis.2023.166883

Source: Biochimica et Biophysica Acta - September 8, 2023 Category: Biochemistry Authors: Pengjiao Xi Wenjuan Zhu Yan Zhang Meng Wang Huimin Liang Haomin Wang Derun Tian Source Type: research