Sex differences in distribution and identity of aromatase gene expressing cells in the young adult rat brain

ConclusionsFemales show overall a lower number of cells expressingCyp19a1 in the limbic brain. In both sexes, aromatase is expressed in a region-specific manner in GABAergic and glutamatergic neurons. These findings call for investigations of the relevance of sex-specific and region-dependent expression ofCyp19a1 in the limbic brain to sex differences in behavior and mental health.

http://link.springer.com/10.1186/s13293-023-00541-8

Source: Biology of Sex Differences - September 1, 2023 Category: Biology Source Type: research