Jianpi Decoction Combined with Medroxyprogesterone Acetate Alleviates Cancer Cachexia and Prevents Muscle Atrophy by Directly Inhibiting E3 Ubiquitin Ligase

CONCLUSIONS: Administration of JP combined with MPA restores tumor-induced cachexia conditions. In addition, the profound effect of JP combined with MPA on tumor-induced cachexia may be due to its inhibition of muscle proteolysis (E3 ubiquitinase system).PMID:37612478 | DOI:10.1007/s11655-023-3702-4

Source: Cancer Control - August 23, 2023 Category: Cancer & Oncology Authors: Qi Li Zhao-di Kong Huan Wang Hong-Hui Gu Zhong Chen Shi-Guang Li Yi-Qi Chen Yu Cai Zhen-Jiang Yang Source Type: research