The variability of PNPLA3 gene as a potential marker of cold adaptation in Yakuts
In this study, we identified two major diplotypes [GG][GG] and [CG][GG]. The high frequency of the mutant rs738409: G variant in Yakuts may be an adaptation of the organism to low temperatures. The study of the adiponutringene may be an important key to understanding the mechanisms of adaptation to low temperatures and metabolic processes in the indigenous population of the North.PMID:37581274 | PMC:PMC10431738 | DOI:10.1080/22423982.2023.2246647
Source: International Journal of Circumpolar Health - Category: International Medicine & Public Health Authors: Nadezhda Ivanovna Pavlova Alexey Alexeevich Bochurov Vladislav Amirovich Alekseev Lyubov Akhmedovna Sydykova Vladimir Vladimirovich Dodokhov Khariton Alekseevich Kurtanov Alexey Vasilievich Krylov Source Type: research