Expression Profile, Molecular Association, and Clinical Significance of POLD4 in Glioblastoma

In conclusion, POLD4 is significantly upregulated in glioblastoma and may be used as a potential diagnostic or prognostic biomarker for GBM patients. However, to establish the same a large cohort study is needed. Using TCGA data and various cancer bioinformatics tools mentioned above we observed very high level of gene and protein expression of POLD4 in glioblastoma patients. The expression of POLD4 was significantly correlated with inflammatory and oncogenic pathways and it also has a significant correlation with adverse outcome in patients with glioblastoma.PMID:37543966 | DOI:10.1007/s10571-023-01393-x
Source: Cellular and Molecular Neurobiology - Category: Cytology Authors: Source Type: research