Efficacy and safety of tramadol in the treatment of opioid withdrawal: A meta-analysis of randomized controlled trials

CONCLUSION: Authors conclude that the efficacy of tramadol in reducing opioid withdrawal symptoms is not significantly different from comparators with low certainty of evidence against placebo, moderate against methadone, whereas with high certainty of evidence against buprenorphine and clonidine.PMID:37517376 | DOI:10.1016/j.addbeh.2023.107815

Source: Addictive Behaviors - July 30, 2023 Category: Addiction Authors: Milan Padhan Rituparna Maiti Debadatta Mohapatra Biswa Ranjan Mishra Source Type: research