Spread of multidrug resistance in non-PCV13/PCV20 serotypes of Streptococcus pneumoniae: A cross-sectional study ten years after the introduction of pneumococcal conjugate vaccine in Japan

J Microbiol Immunol Infect. 2023 Jul 20:S1684-1182(23)00123-8. doi: 10.1016/j.jmii.2023.07.004. Online ahead of print.ABSTRACTTen years after the introduction of the pneumococcal conjugate vaccine (PCV) in Japan, the prevalence rates of non-PCV13 and non-PCV20 serotypes among pediatric pneumococcal isolates were 94.0% and 73.7%, respectively. The predominant non-PCV13/PCV20 serotypes (15A, 35B, and 23A) were mostly multidrug-resistant (≥80.5%), exhibiting non-susceptibility to penicillin.PMID:37517964 | DOI:10.1016/j.jmii.2023.07.004

Source: Journal of Microbiology, Immunology, and Infection - July 30, 2023 Category: Microbiology Authors: Mitsuyo Kawaguchiya Noriko Urushibara Meiji Soe Aung Nobuhide Ohashi Rika Takamatsu Sho Tsutida Masahiko Ito Nobumichi Kobayashi Source Type: research