One Pill for Everyone? Twenty Years of Polypill for Cardiovascular Disease

The concept of the polypill was first proposed in 2003 as a strategy to reduce cardiovascular risk by combining multiple therapeutic agents into a single daily pill. Wald and Law estimated that a combination of a statin, thiazide diuretic, β blocker, angiotensin converting enzyme (ACE) inhibitor, folic acid, and aspirin could reduce ischemic heart disease events and stroke by 88% and 80%, respectively.1 Because rates of cardiovascular disease (CVD) remain high worldwide, the polypill or fixed dose combination strategy is viewed as a potential method to reduce barriers to adequate medical care.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research