Dose-dependent effects of acetaminophen and ibuprofen on mitochondrial respiration of human platelets

In conclusion, platelets from healthy donors represents a population of cells easily available, which can be routinely used in studies assessing mitochondrial drug toxicity. Whether these results can be recapitulated in patients treated with these medications is worth further investigation as potential peripheral biomarker of drug overdose.PMID:37486451 | DOI:10.1007/s11010-023-04814-z
Source: Molecular and Cellular Biochemistry - Category: Biochemistry Authors: Source Type: research