Comprehensive analysis of ferroptosis-related hub gene signatures as a potential pathogenesis and therapeutic target for systemic sclerosis: A bioinformatics analysis

Conclusions: Necroptosis and ferroptosis were upregulated in patients with SSc and involved in modulating cell proliferation, differentiation, and migration. IL-6 and CYBB are key ferroptosis-related genes in SSc. Ferroptosis and related genes might be promising targets in the treatment of SSc.PMID:37403234 | PMC:PMC10331081 | DOI:10.1177/03946320231187783

Source: International Journal of Immunopathology and Pharmacology - July 5, 2023 Category: Allergy & Immunology Authors: Chenmin Wu Jianwen Liu Zhihan Chen Yanfang Wu Fei Gao Source Type: research