Cancers, Vol. 15, Pages 3663: The Prevalence and Molecular Landscape of Lynch Syndrome in the Affected and General Population
Conclusion: The most common genes affected in the diagnostic and EstBB cohorts were MLH1 and PMS2 genes, respectively. The LS diagnosis mean age was 44.8 years for index cases and 36.8 years (p = 0.003) for family members. In the MMR IHC pilot study, 29% had LS.
Source: Cancers - Category: Cancer & Oncology Authors: Laura Roht Piret Laidre Mikk Tooming Neeme T õnisson Margit N õukas Miriam Nurm Estonian Biobank Research Team Hanno Roomere Kadri Rekker Kadri Toome Olga Fjodorova Ülle Murumets Ustina Šamarina Sander Pajusalu Anu Aasp õllu Liis Salum äe Kristina Tags: Review Source Type: research
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