Exploratory Multisite MR Spectroscopic Imaging Shows White Matter Neuroaxonal Loss Associated with Complications of Type 1 Diabetes in Children [FUNCTIONAL]

CONCLUSIONS:
Our pilot study suggests that MRSI differentiates GM and WM by NAA/Cr in this population, disease complications may lead to neuroaxonal loss in WM in children, and deeper investigation is warranted to further untangle how diabetic ketoacidosis and chronic hyperglycemia affect brain health and cognition in type 1 diabetes.

Source: American Journal of Neuroradiology - July 10, 2023 Category: Radiology Authors: Cai, L. Y., Tanase, C., Anderson, A. W., Patel, N. J., Lee, C. A., Jones, R. S., LeStourgeon, L. M., Mahon, A., Taki, I., Juvera, J., Pruthi, S., Gwal, K., Ozturk, A., Kang, H., Rewers, A., Rewers, M. J., Alonso, G. T., Glaser, N., Ghetti, S., Jaser, S. S Tags: FUNCTIONAL Source Type: research