Review: Targeting EZH2 in Neuroblastoma

Neuroblastoma is the most common extra-cranial solid tumor with up to 100 children newly diagnosed annually in the UK [1]. Around 40% of patients are diagnosed before 1 year old and the median age at diagnosis is 17-18 months [2]. Neuroblastoma is an embryonal tumor of the sympathetic nervous system arising from immature neural crest cells [3]. It generally originates in the adrenal glands (65%), however, it can arise from anywhere containing sympathetic nervous tissue, including the chest (20%), neck (5%) and pelvis (5%) [4].
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Anti-tumour Treatment Source Type: research