Glucose-stimulated insulin secretion depends on FFA1 and Gq in neonatal mouse islets

Conclusions/interpretationFFA1 promotes glucose-responsive insulin secretion and functional maturation of newborn islets and is required for adaptive offspring insulin secretion in the face of metabolic challenge, such as parental HFD.Graphical Abstract
Source: Diabetologia - Category: Endocrinology Source Type: research