Onconephrology and Thrombotic Microangiopathy: Looking Beyond the Horizon

Thrombotic microangiopathies (TMAs) represent a complex interaction of endothelial and podocyte biology, nephron physiology, complement genetics, and oncologic therapies with host immunology. The complexity of various factors, such as molecular causes, genetic expressions, and immune system mimicking, along with incomplete penetrance, make it difficult to find a straightforward solution. As a result, there may be variations in diagnosis, study, and treatment approaches, and achieving a consensus can be challenging.
Source: Seminars in Nephrology - Category: Urology & Nephrology Authors: Source Type: research