Identification of potent target and its mechanism of action of Tripterygium wilfordii Hook F in the treatment of lupus nephritis

ConclusionThe mRNA expression profile of renal tissue from LN patients revealed a large number of DEGs. TWHF has been shown to interact with the DEGs (including HMOX1, ALB and CASP1) through hydrogen bonding to treat LN.

Source: International Journal of Rheumatic Diseases - June 15, 2023 Category: Rheumatology Authors: Bin Cai, Hongjuan Lu, Qianyi Ye, Qingqing Xiao, Xin Wu, Huji Xu Tags: ORIGINAL ARTICLE Source Type: research