Anti-vascular endothelial growth factors in combination with vitrectomy for complications of proliferative diabetic retinopathy

CONCLUSIONS: The perioperative use of anti-VEGF reduces the risk of late POVCH, probably results in lower early POVCH risk and may improve visual outcomes. It also reduces the incidence of intraoperative retinal breaks. The evidence is very uncertain about its effect on the need for silicone oil tamponade. The reported complications from its use appear to be low. Agreement on variables included and outcome standardisation is required in trials studying vitrectomy for PDR.PMID:37260074 | PMC:PMC10230853 | DOI:10.1002/14651858.CD008214.pub4
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Source Type: research