Treatments for relapsed, BRCA-wild type, platinum-sensitive ovarian cancer: A systematic review and network meta-analysis

Epithelial ovarian cancer includes different histotypes: high-grade serous, low-grade serous, mucinous, clear cell, and endometrioid. The aim of ovarian cancer treatment is complete remission through surgery and the administration of chemotherapy (CT), usually carboplatin in combination with paclitaxel +/- bevacizumab). First-line treatment for advanced ovarian cancer can be followed by relapse (occurring in approximately 70% of patients within 3 years of first-line treatment)1 and is characterized by a dismal prognosis for stage III (5-year survival rate:20%) and stage IV (5-year survival rate:5%)2.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Systematic or Meta-analysis Studies Source Type: research