G protein-coupled receptor 158 modulates sensitivity to the sedative-hypnotic effect of ethanol in male mice

CONCLUSIONS: This study reveals a critical role of neuronal GPR158 in shaping sensitivity to the sedative-hypnotic effect of ethanol, suggesting that GPR158 may be a potential target for treating alcohol use disorder.PMID:37128649 | DOI:10.1111/acer.15094

Source: Alcoholism, Clinical and Experimental Research - May 2, 2023 Category: Addiction Authors: Shoupeng Wei Lei Zheng Jinlong Chang Jian Jiang Zhiyu Zhou Huanquan Liao Kun Song Xiaoma Liu Xinjin Chi Huiliang Li Xin Kuang Ningning Li Source Type: research