Impact of prior systemic therapy on lymphocytic infiltration in surgically resected breast cancer brain metastases

ConclusionsThis observation suggests that systemic therapy may interfere with the immune response to BCBMs and cause exhaustion of anti-tumor immunity. This motivates clinical investigation of strategies to enhance LI for therapeutic benefit to improve outcomes for patients with BCBMs.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research