Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity

Conclusion
These results suggest that the housing environment in which gnotobiotic mice are maintained post-FMT strongly influences gut microbiota composition and function and can lead to distinctive phenotypes in recipient mice. Better standardisation of FMT experiments is needed to ensure reproducible and translatable results.

Source: Gut - April 4, 2023 Category: Gastroenterology Authors: Daoust, L., Choi, B. S.-Y., Agrinier, A.-L., Varin, T. V., Ouellette, A., Mitchell, P. L., Samson, N., Pilon, G., Levy, E., Desjardins, Y., Laplante, M., Anhe, F. F., Houde, V. P., Marette, A. Tags: Gut Gut microbiota Source Type: research