Muscle Sodium Accumulation in Kidney Failure: Physiological Impact and Mitigation Strategies

Skeletal muscle has recently been recognized as a nonosmotic sodium reservoir that buffers dietary sodium. The in-vivo quantification of muscle sodium is based on a novel technology, sodium magnetic resonance imaging (23Na-MRI). Studies using this technology have shown that muscle sodium accumulation may be a clinical complication of chronic kidney disease (CKD). This review aims to summarize existing evidence on muscle sodium accumulation in patients with CKD and to identify knowledge gaps and topics for further research.
Source: Journal of Renal Nutrition - Category: Urology & Nephrology Authors: Source Type: research