Ginaton reduces M1-polarized macrophages in hypertensive cardiac remodeling via NF- κB signaling

Conclusion: Our study showed that Ginaton treatment inhibits Ang II-induced M1 phenotype macrophage activation, macrophage adhesion, and mitigation, as well as the inflammatory response leading to impaired and dysfunctional hypertension and cardiac remodeling. Gianton may be a powerful treatment for heart disease.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research