Dietary omega-3 fatty acid deficiency from pre-pregnancy to lactation affects expression of genes involved in hippocampal neurogenesis of the offspring

For optimal growth, the fetal brain requires maternal long-chain polyunsaturated fatty acids (LCPUFAs) via the placenta and breast milk in utero and postnatally, respectively [1 –3]. Maternal PUFAs support fetal growth and brain development [4,5]. Maternal PUFAs are important for the overall development of the fetus, including lactating mammary gland [6]. The mammary gland is an active lipid synthetic organ that secretes many milk lipids during the 20-d lactation cycle in mice. Its development is comparable between humans and rodents.

Source: Prostaglandins, Leukotrienes and Essential Fatty Acids - March 11, 2023 Category: Biomedical Science Authors: Vilasagaram Srinivas, Saikanth Varma, Suryam Reddy Kona, Ahamed Ibrahim, Asim K Duttaroy, Sanjay Basak Tags: Original research article Source Type: research