Vaccinomics: A scoping review

CONCLUSION: This scoping review identified numerous genetic associations with vaccine immunogenicity and several genetic associations with vaccine safety. Most associations were only reported in one study. This illustrates both the potential of and need for investment in vaccinomics. Current research in this field is focused on systems and genetic-based studies designed to identify risk signatures for serious vaccine reactions or diminished vaccine immunogenicity. Such research could bolster our ability to develop safer and more effective vaccines.PMID:36803903 | DOI:10.1016/j.vaccine.2023.02.009

Source: Vaccine - February 21, 2023 Category: Allergy & Immunology Authors: Matthew Z Dudley Jennifer E Gerber Haley Budigan Ni Madeleine Blunt Taylor A Holroyd Bruce C Carleton Gregory A Poland Daniel A Salmon Source Type: research