Deciphering the pharmacological mechanism of the Chinese formula Huanglian-Jie-Du decoction in the treatment of ischemic stroke using a systems biology-based strategy.

CONCLUSION: This study has developed for the first time a comprehensive systems approach integrating drug target prediction, network analysis and molecular docking simulation to reveal the relationships between the herbs contained in HLJDD and their putative targets and ischemic stroke-related pathways. PMID: 25937634 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/25937634?dopt=Abstract

Source: Acta Pharmacologica Sinica - May 4, 2015 Category: Drugs & Pharmacology Authors: Zhang YQ, Wang SS, Zhu WL, Ma Y, Zhang FB, Liang RX, Xu HY, Yang HJ Tags: Acta Pharmacol Sin Source Type: research