Surgical decompression for malignant cerebral oedema after ischaemic stroke

CONCLUSIONS: Surgical decompression improves outcomes in the management of malignant oedema after acute ischaemic stroke, including a considerable reduction in death or severe disability (mRS > 4) and a reduction in death or moderate disability (mRS > 3). Whilst there is evidence that this positive treatment effect is present in patients > 60 years old, it is important to take into account that these patients have a poorer prospect of functional survival independent of this treatment effect. In interpreting these results it must also be considered that the data demonstrating benefit are drawn from a unique patient subset with profound neurological deficit, reduced level of consciousness, and no pre-morbid disability or severe comorbidity.PMID:36385224 | DOI:10.1002/14651858.CD014989.pub2

Source: Cochrane Database of Systematic Reviews - November 17, 2022 Category: General Medicine Authors: Ashraf Dower Michael Mulcahy Monish Maharaj Hui Chen Chi Eung Danforn Lim Yingda Li Mark Sheridan Source Type: research